Health Library

The Health Library is a collection of health and wellness resources created for learning and accessibility. Select a topic below for related health information or search for a topic in the search bar for more information on other medical conditions.

Spanish Translation

Top of the page

Familial atypical multiple mole and melanoma (FAMMM) syndrome

Familial atypical multiple mole and melanoma (FAMMM) syndrome is an inherited tendency to develop melanoma.

FAMMM syndrome is present when:

  • Melanoma has been diagnosed in a family member, including grandparents, aunts, uncles, and cousins.
  • Several family members have large numbers of moles (often more than 50), some of which may be abnormal, or atypical, moles.

Some people with FAMMM syndrome have certain gene changes that also increase their risk for other cancers, such as pancreatic cancer.

Current as of: May 1, 2026

Author: WebMD Ignite Staff

Clinical Review Board
All WebMD Ignite education is reviewed by a team that includes physicians, nurses, advanced practitioners, registered dieticians, and other healthcare professionals.

This information does not replace the advice of a doctor. WebMD Ignite, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.