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Pronunciation: GA ni REL ix

Brand: Ganirelix Acetate

What is the most important information I should know about ganirelix?

Tell your doctor if you have a severe or active allergy.

What is ganirelix?

Ganirelix reduces certain hormones in the body, including estrogen.

Ganirelix is used with other medicines to treat infertility in women.

Ganirelix may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before using ganirelix?

You should not use this medicine if you are allergic to ganirelix or similar medications such as leuprolide, goserelin, or nafarelin.

Tell your doctor if you are allergic to latex rubber, or if you have a severe or active allergy.

May cause birth defects. Do not use if you are pregnant. You may need to have a negative pregnancy test before starting this treatment. Tell your doctor if you become pregnant.

You should not breastfeed while using ganirelix.

How should I use ganirelix?

Ganirelix is injected under the skin, usually once daily for several days in a row during certain phases of your fertility treatment cycle.

Prepare an injection only when you are ready to give it. Read and follow all Instructions for Use. Ask your doctor or pharmacist if you need help.

Do not reuse a needle or syringe. Place them in a puncture-proof "sharps" container and dispose of it following state or local laws. Keep out of the reach of children and pets.

Your blood may need to be tested often. Remain under the care of a doctor while using ganirelix.

Store the prefilled syringe at room temperature, away from heat, moisture and light.

Throw away a prefilled syringe after one use, even if there is still medicine left inside.

What happens if I miss a dose?

Call your doctor for instructions if you miss a dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while using ganirelix?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What are the possible side effects of ganirelix?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Some women using this medicine develop ovarian hyperstimulation syndrome (OHSS), a potentially life-threatening condition. Call your doctor right away if you have symptoms of OHSS:

  • stomach pain, bloating, nausea, vomiting, diarrhea;
  • rapid weight gain, especially in your face and midsection;
  • little or no urination; or
  • pain when you breathe, rapid heart rate, feeling short of breath (especially when lying down).

Common side effects may include:

  • stomach pain;
  • headache;
  • vaginal bleeding; or
  • OHSS.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect ganirelix?

Other drugs may affect ganirelix, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

Where can I get more information?

Your pharmacist can provide more information about ganirelix.

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