Chronic Kidney Disease: Medicines to Be Careful With
Many medicines may impair kidney function and cause kidney damage. If you have chronic kidney disease, your doctor may advise you to continue to take a medicine but may change how much you take. Or you may change to a different medicine. Make sure you talk with your doctor before you start or stop any medicine.
Medicines that may need to be avoided, adjusted, or changed include:
- Pain medicines, including:
- Nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen and naproxen.
- Acetaminophen and aspirin. These may be harmful if overused. They are usually safe in small amounts.
- Herbal supplements. They can contain minerals like potassium that are harmful for people who have kidney disease. Many herbs can interact with prescription medicines.
- Diabetes medicines, including insulin and metformin.
- Heartburn and upset-stomach medicines, such as Milk of Magnesia and Alka-Seltzer.
- Antimicrobial medicines, including some antibiotics, anti-fungal, and antiviral medicines.
Credits
Current as of: December 15, 2025
Author: Ignite Healthwise, LLC Staff
Clinical Review Board
All Ignite Healthwise, LLC education is reviewed by a team that includes physicians, nurses, advanced practitioners, registered dieticians, and other healthcare professionals.